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HRID575194

反应详情

EQUATION

反应方程式

HRID 575194 的结构方程式

REACTANTS

反应物

2
结构：C#CC1(O)CCCN(C)C1=O
HCID86669576

未命名化合物

2 次

结构：NC(=O)c1cn2c(n1)-c1cc(Br)c(F)cc1OCC2
HCID86693051

未命名化合物

PRODUCTS

生成物

1
结构：CN1CCCC(O)(C#Cc2cc3c(cc2F)OCCn2cc(C(N)=O)nc2-3)C1=O
HCID86693200

未命名化合物

收率 16%

PROCEDURE

实验过程

Similar to as described in General Procedure G, 10-bromo-9-fluoro-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamide was reacted with 3-ethynyl-3-hydroxy-1-methylpiperidin-2-one (US2012/214762A 1) to give the titled compound as a white solid (20 mg, 16%).