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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 575197Generated: October 30, 2026

(R)-2-(5-methylisoxazol-3-yl)but-3-yn-2-ol → HCID 86693205, compound

https://huagongshe.com/reaction/575197

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-2-(5-methylisoxazol-3-yl)but-3-yn-2-olHCID 58221468—
ReactantHCID 86693206HCID 86693206—
CatalystHCID 178418397HCID 178418397—
ProductHCID 86693205HCID 8669320521%

Reaction Steps

Similar to as described in General Procedure G with the exception of replacing PdCl2(PPh3)2 with Pd (PPh3)4, 2-chloro-6,7-dihydroimidazo[1,2-d]pyrido[3,2-b][1,4]oxazepine-9-carboxamide was reacted with (R)-2-(5-methylisoxazol-3-yl)but-3-yn-2-ol (US2012/214762A1) to give the titled compound as a white solid (36 mg, 21%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09034866B2
Source datasetuspto-grants-2015_05
ORD IDord-b47192fd376a47b0852dbcc63ab3e830
Source noteuspto-grants-2015_05