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HRID575198

反应详情

EQUATION

反应方程式

HRID 575198 的结构方程式

REACTANTS

反应物

2
结构：C#CC(C)(O)c1cc(C)ccn1
HCID58221648

未命名化合物

结构：NC(=O)c1cn2c(n1)-c1cc(Br)c(F)cc1OCC2
HCID86693051

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccnc(C(C)(O)C#Cc2cc3c(cc2F)OCCn2cc(C(N)=O)nc2-3)c1
HCID86693207

未命名化合物

收率 10%

PROCEDURE

实验过程

Similar to as described in General Procedure G, 10-bromo-9-fluoro-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamide was reacted with 2-(4-methylpyridin-2-yl)but-3-yn-2-ol (WO2009/158011A1) to give the titled compound as a white solid (39 mg, 10%).