Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 575311Generated: October 30, 2026

(R)-2-(5-methylisoxazol-3-yl)but-3-yn-2-ol → HCID 86693343, compound

https://huagongshe.com/reaction/575311

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-2-(5-methylisoxazol-3-yl)but-3-yn-2-olHCID 58221468—
ReactantHCID 86693344HCID 86693344—
ProductHCID 86693343HCID 8669334320%

Reaction Steps

10-bromo-3-(trifluoromethyl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamide was reacted with (2R)-2-(5-methylisoxazol-3-yl)but-3-yn-2-ol via General Procedure E to afford 19 mg (20%) of 10-[(3R)-3-hydroxy-3-(5-methylisoxazol-3-yl)but-1-ynyl]-3-(trifluoromethyl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine-2-carboxamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09034866B2
Source datasetuspto-grants-2015_05
ORD IDord-af4d7739b48e4b4fa3fb54cac8455b5e
Source noteuspto-grants-2015_05