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HRID575475

反应详情

EQUATION

反应方程式

HRID 575475 的结构方程式

REACTANTS

反应物

3
结构：NC(=O)c1nc2n(c1I)C1CC(C1)c1ccc(Br)cc1-2
HCID86693365

未命名化合物

结构：NC(=O)c1nc2n(c1C1CC1)C1CC(C1)c1cc(F)c(Br)cc1-2
HCID86693537

未命名化合物

结构：CC(C)(C)OC(=O)N1CC([Zn+])C1.[I-]
HCID178452187

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CC(c2c(C(N)=O)nc3n2C2CC(C2)c2ccc(Br)cc2-3)C1
HCID86693543

未命名化合物

PROCEDURE

实验过程

Similar to as described for 10-bromo-3-cyclopropyl-9-fluoro-6,7-dihydro-5H-5,7-methanobenzo[c]imidazo[1,2-a]azepine-2-carboxamide above, 10-bromo-3-iodo-6,7-dihydro-5H-5,7-methanobenzo[c]imidazo[1,2-a]azepine-2-carboxamide was coupled with (1-(tert-butoxycarbonyl)azetidin-3-yl)zinc(II) iodide to give the titled compound after purification by flash column chromatography.