HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Ethynylcyclohexanol → 10-((1-hydroxycyclohexyl)ethynyl)-N3-methyl-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2,3-dicarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Ethynylcyclohexanol | HCID 6525 | — |
| Reactant | 10-bromo-N3-methyl-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine-2,3-dicarboxamide | HCID 86693186 | — |
| Product | 10-((1-hydroxycyclohexyl)ethynyl)-N3-methyl-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2,3-dicarboxamide | HCID 86693549 | — |
Reaction Steps
Similar to as described in General Procedure E, reaction of 10-bromo-N3-methyl-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2,3-dicarboxamide with 1-ethynylcyclohexanol gave the titled compound. M+H=409.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09034866B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-9dd1ca529126497591ff5fbf32bea9f8 |
| Source note | uspto-grants-2015_05 |