HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-3-ethynyl-3-hydroxy-1-methylpyrrolidin-2-one → HCID 89755371, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-3-ethynyl-3-hydroxy-1-methylpyrrolidin-2-one | HCID 86693296 | — |
| Reactant | HCID 89754462 | HCID 89754462 | — |
| Product | HCID 89755371 | HCID 89755371 | — |
Reaction Steps
Similar to as described in General Procedure G, racemic 9-iodo-4-hydroxy-4-methyl-4,5-dihydrobenzo[b]pyrazolo[1,5-d][1,4]oxazepine-2-carboxamide was reacted with (R)-3-ethynyl-3-hydroxy-1-methylpyrrolidin-2-one to give a diasteromeric mixture of the titled compound after purification by prep HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09034866B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-8c8f79de14a94c988f337b8463c7e560 |
| Source note | uspto-grants-2015_05 |