Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chloroform → (1-Ethyl-2,2-dimethyl-1,2-dihydroquinol-4-yl)-N-octyl-methanesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chloroform | HCID 6212 | — |
| 반응물 | Octylamine | HCID 8143 | — |
| 반응물 | HCID 12138182 | HCID 12138182 | — |
| 반응물 | (1-Ethyl-2,2-dimethyl-1,2-dihydroquinol-4-yl-methanesulfonyl)-piperidine-4-carboxylic acid methyl ester | HCID 12138183 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | (1-Ethyl-2,2-dimethyl-1,2-dihydroquinol-4-yl)-N-octyl-methanesulfonamide | HCID 12138188 | 81% |
반응 단계
(1-Ethyl-2,2-dimethyl-1,2-dihydroquinol-4-yl)-N-octyl-methanesulfonamide (12) is prepared similarly to compound (10) using compound (9) with n-octylamine. The product is isolated by column chromatography on silica gel with a gradient running from chloroform to ethanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09035042B2 |
| 출처 데이터셋 | uspto-grants-2015_05 |
| ORD ID | ord-c6d1e24b56544e20805d969f7d238dd7 |
| 출처 메모 | uspto-grants-2015_05 |