HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylsulfonylaminophenylboronic acid → N-[3-(1-methyl-6-oxopyridin-3-yl)phenyl]methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylsulfonylaminophenylboronic acid | HCID 2773535 | — |
| Reactant | 5-Bromo-1,4-dimethyl-1,2-dihydropyridin-2-one | HCID 67281826 | — |
| Product | N-[3-(1-methyl-6-oxopyridin-3-yl)phenyl]methanesulfonamide | HCID 118021604 | — |
Reaction Steps
5-Bromo-1,4-dimethylpyridin-2-one was treated with [3-(methanesulfonamido)phenyl]boronic acid in a manner similar to Example 94 to give the title compound as a white solid. 1H NMR (CDCl3, 400 MHz) δ 7.43 (t, J=8.0 Hz, 1H), 7.20 (d, J=8.0 Hz, 1H), 7.16 (s, 1H), 7.07 (d, J=7.6 Hz, 1H), 6.71 (s, 1H), 6.69 (s, 1H), 3.67 (s, 3H), 3.07 (s, 3H), 2.16 (s, 3H). LCMS (M+H)+ 293.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09034900B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-6a63781dfa214941883f9abcc43ce25f |
| Source note | uspto-grants-2015_05 |