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HRID57573

反应详情

EQUATION

反应方程式

HRID 57573 的结构方程式

REACTANTS

反应物

2
结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：COC(=O)C1CCN(c2ccc([N+](=O)[O-])cc2)CC1
HCID345002

methyl 1-(4-nitrophenyl)piperidine-4-carboxylate

C13H16N2O4

PRODUCTS

生成物

1
结构：O=C(O)C1CCN(c2ccc([N+](=O)[O-])cc2)CC1
HCID2767265

1-(4-nitrophenyl)piperidine-4-carboxylic acid

C12H14N2O4

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CO
溶剂HCID887

Methanol

CH4O

结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

A solution of methyl 1-(4-nitrophenyl)piperidine-4-carboxylate (3.84 g, 14.53 mmol) and NaOH (0.87 g, 21.79 mmol) in 15 mL of MeOH and 5 mL of water was stirred at room temperature for 3 hours. The volatiles were removed in vacuo to give 1-(4-nitrophenyl)piperidine-4-carboxylic acid.

WORKUP

后处理

  1. customThe volatiles were removed in vacuo