4-(Dimethylamino)phenylboronic acid → 3-(7-(4-(Dimethylamino)phenyl)pyrido[4,3-b]pyrazin-5-ylamino)propanamide

HRID 57628Notes

Reaction equation

HRID 57628 reaction equation
Cl[C:2]1[N:11]=[C:10]([NH:12][CH2:13][CH2:14][C:15]([NH2:17])=[O:16])[C:9]2[C:4](=[N:5][CH:6]=[CH:7][N:8]=2)[CH:3]=1.[CH3:18][N:19]([CH3:29])[C:20]1[CH:25]=[CH:24][C:23](B(O)O)=[CH:22][CH:21]=1>>[CH3:18][N:19]([CH3:29])[C:20]1[CH:25]=[CH:24][C:23]([C:2]2[N:11]=[C:10]([NH:12][CH2:13][CH2:14][C:15]([NH2:17])=[O:16])[C:9]3[C:4](=[N:5][CH:6]=[CH:7][N:8]=3)[CH:3]=2)=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 27343444-(Dimethylamino)phenylboronic acidHCID 867173893-(7-Chloropyrido[4,3-b]pyrazin-5-ylamino)propanamide

Product 1

HCID 711134573-(7-(4-(Dimethylamino)phenyl)pyrido[4,3-b]pyrazin-5-ylamino)propanamide

Procedure

The title compound was prepared according to the procedure of Compound 1 (B) using 3-(7-chloropyrido[4,3-b]pyrazin-5-ylamino)propanamide prepared above and 4-(dimethylamino)phenylboronic acid. MS (m/z): 337 (M+H)+.

Sources & evidence

ORD record
ord-bbbcd5d67a994780aeaa445047ff21b0
Source dataset
uspto-grants-2016_09
Patent number
US09434726B2

Reaction notes

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