HCID 89253186, compound → HCID 86714087, compound

HRID 576409Notes

Reaction equation

BrC1C([C@H:8]2[C@H:13]([O:14][CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[C@@H:12]([O:22][CH2:23][C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[C@H:11]([O:30][CH2:31][C:32]3[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=3)[C@@H:10]([CH2:38][O:39][CH2:40][C:41]3[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=3)[O:9]2)=CC(CC2C=CC(CC)=CC=2)=C(Cl)C=1O.[CH2:58]([O:61][C:62]1[C:67]([O:68][CH2:69][CH:70]=[CH2:71])=[C:66]([Cl:72])[C:65]([CH2:73][C:74]2[CH:79]=[CH:78][C:77]([O:80][CH2:81][CH3:82])=[CH:76][CH:75]=2)=[CH:64][C:63]=1Br)[CH:59]=[CH2:60]>>[CH2:31]([O:30][C@H:11]1[C@H:12]([O:22][CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C@@H:13]([O:14][CH2:15][C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)[C@H:8]([C:63]2[CH:64]=[C:65]([CH2:73][C:74]3[CH:79]=[CH:78][C:77]([O:80][CH2:81][CH3:82])=[CH:76][CH:75]=3)[C:66]([Cl:72])=[C:67]([O:68][CH2:69][CH:70]=[CH2:71])[C:62]=2[O:61][CH2:58][CH:59]=[CH2:60])[O:9][C@@H:10]1[CH2:38][O:39][CH2:40][C:41]1[CH:42]=[CH:43][CH:44]=[CH:45][CH:46]=1)[C:32]1[CH:33]=[CH:34][CH:35]=[CH:36][CH:37]=1

Participants

Reactant 2

HCID 89253186HCID 89253186, compound

HCID 90073316HCID 90073316, compound

Product 1

HCID 86714087HCID 86714087, compound

Procedure

Similar procedure with preparation of 162 proceeded except for using compound 202 to obtain the compound 203.

Sources & evidence

ORD record: ord-4f9b5a1ea76547c2b80d9960e6ed3be7
Source dataset: uspto-grants-2015_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09034921B2

Reaction notes

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