HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 576481Generated: October 31, 2026
Acetic Acid → 4-(3-Hydroxyphenylthio)-2,5-xylidine
https://huagongshe.com/reaction/576481
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | 2-Nitro-5-(3-hydroxyphenylthio)-p-xylene | HCID 66583860 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-(3-Hydroxyphenylthio)-2,5-xylidine | HCID 86687808 | — |
Reaction Steps
6.3 ml of glacial acetic acid (0.11 moles) are added to a solution of 20 g of the product obtained in Example 4 (0.076 moles) in 328 ml of ethanol and 33 ml of H2O; 29.7 g of Fe in powder form (0.53 moles) are carefully added to the reaction mixture kept under stirring at 60° C. The temperature is brought to 90° C. and the mixture is kept under stirring for 1.5 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09040457B2 |
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| Source dataset | uspto-grants-2015_05 |
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| ORD ID | ord-c01d0464b83c46f4bf79b918a41a0202 |
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| Source note | uspto-grants-2015_05 |
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