Hydrochloric Acid → (S)-methyl 2-((2-aminobutyl)amino)-2-oxoacetate hydrochloride

Participants

Reaction Steps

To an ice cold solution of 4M HCl in dioxane (20 mL) was added (S)-methyl 2-((2-((tert-butoxycarbonyl)amino)butyl)amino)-2-oxoacetate (1.3 g, 4.6 mmol). After 30 minutes, the reaction mixture was concentrated to provide a yellow foam (968 mg, 100%), which was used without further purification. MS (ESI): mass calcd. for C7H14N2O3, 174.1; m/z found, 175.2 [M+H]+.

Provenance & Evidence