(S)-N-Cbz-1,1-diethoxypropan-2-amine → (2S)-1,1-Diethoxy-2-propanamine

To a solution of (S)-benzyl 1,1-diethoxypropan-2-ylcarbamate (Compound XX-1) 844 mg (3.00 mmol) in methanol 50 ml, 5% palladium on carbon 30 mg was added and the mixture was stirred at room temperature for 2 hours under hydrogen atmosphere. The reaction mixture was filtered on celite and washed with methanol 200 ml and the mother solution was concentrated in vacuo to obtain the title compound 442 mg (1000).

1. filtrationThe reaction mixture was filtered on celite
2. washwashed with methanol 200 ml
3. concentrationthe mother solution was concentrated in vacuo

ORD record

ord-4c1dd4bb8ac34f2c81417c6e40c68a46

Source dataset

uspto-grants-2015_05

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US09040531B2