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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 576871Generated: October 30, 2026

HCID 86663943, compound → HCID 66644582, compound

https://huagongshe.com/reaction/576871

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86663943HCID 86663943—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 66644582HCID 6664458288%

Reaction Steps

To a solution of (S)-benzyl 1-((2,2-diethoxyethyl) (3-phenylpropyl)amino)-3-(naphthalen-1-yl)-1-oxopropan-2-ylcarbamate (Compound XV-32) 21.4 g (36.8 mmol) in methanol 200 ml, 10% of palladium on carbon (8 g) was added, then the mixture was stirred at H2 atmosphere overnight. The mixture was filtered and the filtrate was evaporated to obtain the title compound 14.5 g (yield 88%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09040531B2
Source datasetuspto-grants-2015_05
ORD IDord-fedbb5c7d7f74199bd5ffa074fe2d2b9
Source noteuspto-grants-2015_05