HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86663943, compound → HCID 66644582, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86663943 | HCID 86663943 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 66644582 | HCID 66644582 | 88% |
Reaction Steps
To a solution of (S)-benzyl 1-((2,2-diethoxyethyl) (3-phenylpropyl)amino)-3-(naphthalen-1-yl)-1-oxopropan-2-ylcarbamate (Compound XV-32) 21.4 g (36.8 mmol) in methanol 200 ml, 10% of palladium on carbon (8 g) was added, then the mixture was stirred at H2 atmosphere overnight. The mixture was filtered and the filtrate was evaporated to obtain the title compound 14.5 g (yield 88%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040531B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-fedbb5c7d7f74199bd5ffa074fe2d2b9 |
| Source note | uspto-grants-2015_05 |