HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66765592, compound → HCID 66765276, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66765592 | HCID 66765592 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 66765276 | HCID 66765276 | — |
Reaction Steps
3-(4-nitro-1H-pyrazol-1-yl)-1-(piperidin-1-yl)propan-1-one (4.4 mmol) was dissolved in 5 mL methanol and palladium on carbon added under an inert atmosphere. The reaction mixture was stirred overnight at rt under hydrogen atmosphere. The resulting mixture was filtered through Celite and the filtrate concentrated in vacuo to give 3-(4-amino-1H-pyrazol-1-yl)-1-(piperidin-1-yl)propan-1-one in a quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040545B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-47125be2a1b74e73a362c60bdb7f71e7 |
| Source note | uspto-grants-2015_05 |