HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenamine, 4-(4-morpholinyl)- → N-(4-(2-(4-morpholinophenylamino)pyrimidin-4-ylthio)phenyl)acrylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenamine, 4-(4-morpholinyl)- | HCID 75655 | — |
| Reactant | N-(4-(2-chloropyrimidin-4-ylthio)phenyl)acrylamide | HCID 86645568 | — |
| Product | N-(4-(2-(4-morpholinophenylamino)pyrimidin-4-ylthio)phenyl)acrylamide | HCID 59491673 | 54% |
Reaction Steps
In a procedure analogous to Example 8, reaction of N-(4-(2-chloropyrimidin-4-ylthio)phenyl)acrylamide (540 mg, 1.85 mmol) and 4-morpholinoaniline (400 mg, 2.24 mmol) furnished the product (430 mg, 54%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040549B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-8a893a2695d1405789c339d290959c57 |
| Source note | uspto-grants-2015_05 |