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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 577826Generated: October 31, 2026

2,6-Dimethylmorpholine, cis- → 3-chloro-2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-fluorobenzoic acid

https://huagongshe.com/reaction/577826

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethylmorpholine, cis-HCID 641500—
Reactant3-Chloro-2,4-difluorobenzoic acidHCID 2773532—
Product3-chloro-2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-fluorobenzoic acidHCID 67358936—

Reaction Steps

Starting materials: 3-chloro-2,4-difluorobenzoic acid and cis-2,6-dimethylmorpholine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09040528B2
Source datasetuspto-grants-2015_05
ORD IDord-88d0bda3c0484902b8bb7ea26f8f2695
Source noteuspto-grants-2015_05