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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 577838Generated: October 26, 2026

2,4-Difluoro-3-methylbenzoic acid → 2,4-Difluoro-3-methyl-5-(pyrazin-2-ylcarbonyl)benzoic acid

https://huagongshe.com/reaction/577838

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Difluoro-3-methylbenzoic acidHCID 13986837—
ReactantN-Methoxy-N-methylpyrazine-2-carboxamideHCID 22613131—
Product2,4-Difluoro-3-methyl-5-(pyrazin-2-ylcarbonyl)benzoic acidHCID 86658059—

Reaction Steps

Starting materials: 2,4-difluoro-3-methylbenzoic acid (Intermediate 46) and N-methoxy-N-methylpyrazine-2-carboxamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09040528B2
Source datasetuspto-grants-2015_05
ORD IDord-90edfceaaca44857a4b6e1ea05f2eda0
Source noteuspto-grants-2015_05