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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 577843Generated: October 30, 2026

1,3-Thiazole-2-carbaldehyde → HCID 86717855, compound

https://huagongshe.com/reaction/577843

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Thiazole-2-carbaldehydeHCID 2734903—
Reactant(2R,6S)-[6-({[tert-butyl(diphenyl)silyl]oxy}methyl)-2-chloro-3-fluorophenyl]-2,6-dimethylmorpholineHCID 67359669—
ReactantHCID 178418821HCID 178418821—
ProductHCID 86717855HCID 86717855—

Reaction Steps

Starting material: (2R,6S)-4-[6-({[tert-butyl(diphenyl)silyl]oxy}methyl)-2-chloro-3-fluorophenyl]-2,6-dimethylmorpholine (Intermediate 42), 1,3-thiazole-2-carbaldehyde and lithium 2,2,6,6-tetramethylpiperidide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09040528B2
Source datasetuspto-grants-2015_05
ORD IDord-835add043b284ca5ab38c0ac343ff23c
Source noteuspto-grants-2015_05