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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 577844Generated: October 30, 2026

1-Methyl-2-imidazolecarboxaldehyde → HCID 86717856, compound

https://huagongshe.com/reaction/577844

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-2-imidazolecarboxaldehydeHCID 139575—
Reactant(2R,6S)-[6-({[tert-butyl(diphenyl)silyl]oxy}methyl)-2-chloro-3-fluorophenyl]-2,6-dimethylmorpholineHCID 67359669—
ReactantButyllithiumHCID 178418339—
ProductHCID 86717856HCID 86717856—

Reaction Steps

Starting material: (2R,6S)-4-[6-({[tert-butyl(diphenyl)silyl]oxy}methyl)-2-chloro-3-fluorophenyl]-2,6-dimethylmorpholine (Intermediate 42), 1-methyl-imidazole-2-carbaldehyde and n-BuLi

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09040528B2
Source datasetuspto-grants-2015_05
ORD IDord-54311dc932314d51a0d931384ff625d2
Source noteuspto-grants-2015_05