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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 577890Generated: October 30, 2026

(2R,6S)-4-(2-((tert-Butyldiphenylsilyloxy)methyl)-4-chloro-5-fluoropyridin-3-yl)-2,6-dimethylmorpholine → HCID 67357699, compound

https://huagongshe.com/reaction/577890

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2R,6S)-4-(2-((tert-Butyldiphenylsilyloxy)methyl)-4-chloro-5-fluoropyridin-3-yl)-2,6-dimethylmorpholineHCID 67319975—
ReactantHCID 86717863HCID 86717863—
ProductHCID 67357699HCID 67357699—

Reaction Steps

Starting material: (2-((tert-butyldiphenylsilyloxy)methyl)-4-chloro-5-fluoropyridin-3-yl)-2,6-dimethylmorpholine (Intermediate 45) and N-methoxy-N,4-dimethylthiazole-2-carboxamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09040528B2
Source datasetuspto-grants-2015_05
ORD IDord-36a4997313fa41e4b51a2c070f85beee
Source noteuspto-grants-2015_05