1-Benzyl-4-piperidylamine → HCID 178469876, compound
Reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:11](=[O:12])[N:10]2[N:13]=[C:14]([C:16]([OH:18])=O)[CH:15]=[C:9]2[NH:8][CH:7]=1)=[O:5])[CH3:2].[CH2:19]([N:26]1[CH2:31][CH2:30][CH:29]([NH2:32])[CH2:28][CH2:27]1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH2:1]([O:3][C:4]([C:6]1[C:11](=[O:12])[N:10]2[N:13]=[C:14]([C:16](=[O:18])[NH:32][CH:29]3[CH2:30][CH2:31][N:26]([CH2:19][C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)[CH2:27][CH2:28]3)[CH:15]=[C:9]2[NH:8][CH:7]=1)=[O:5])[CH3:2]Participants
3
Procedure
The expected compound was obtained according to general procedure F using Key Intermediate V and 1-benzyl-piperidin-4-ylamine. The expected compound was isolated as white powder.
Sources & evidence
- ORD record
- ord-efa1373906ad4ca986b03f062d49c42a
- Source dataset
- uspto-grants-2016_09
- Patent number
- US09434745B2
Reaction notes
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