HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 67432965, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 67431695 | HCID 67431695 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67432965 | HCID 67432965 | — |
Reaction Steps
Starting materials: 1-[(2R,4S,4aS)-rel-11-fluoro-2,4-dimethyl-2′,4′,6′-trioxo-1,1′,2,3′,4,4′,4a,6′-octahydro-2′H,6H-spiro[1,4-oxazino[4,3-a][1,2]oxazolo[4,5-g]quinoline-5,5′-pyrimidin]-8-yl]-1H-pyrazole-4-carboxylic acid (Example 186) and saturated NH3 in THF (2 mL). Purification by reverse phase HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040528B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-27d248ee659448bb9671445f5890e9b8 |
| Source note | uspto-grants-2015_05 |