1-Chloro-N,N-2-trimethylpropenylamine → HCID 86665216, compound

Participants

Reaction Steps

The product obtained at (656b) (15.5 g, 2.97 mmol) in 3 mL THF was combined with (1-Chlor-2-methyl-prop-1-en-1-yl)-dimethylamine (0.14 mL, 1.1 mmol) and stirred at ambient temperature for 1 h. Then a mixture of 2-amino-6-dimethylamino-4-trifluoromethyl-pyridine (0.19 g, 0.94 mmol) with TEA (0.50 mL, 3.6 mmol) in 5 mL THF was added and the mixture stirred at ambient temperature for 16 h. The mixture was filtered, evaporated, the residue was mixed with diethylether, filtered off, washed with diethylether and dried.

Provenance & Evidence