Sodium Hydroxide → 4-Amino-2-methoxy-5-nitrobenzoic acid

HRID 578061Notes

Reaction equation

HRID 578061 reaction equation

C([NH:4][C:5]1[C:14]([N+:15]([O-:17])=[O:16])=[CH:13][C:8]([C:9]([O:11]C)=[O:10])=[C:7]([O:18][CH3:19])[CH:6]=1)(=O)C.[OH-].[Na+]>C(O)C>[NH2:4][C:5]1[C:14]([N+:15]([O-:17])=[O:16])=[CH:13][C:8]([C:9]([OH:11])=[O:10])=[C:7]([O:18][CH3:19])[CH:6]=1

Participants

4

Reactant 2

HCID 14798Sodium Hydroxide

HCID 77723Methyl 4-acetamido-2-methoxy-5-nitrobenzoate

Product 1

HCID 1010164-Amino-2-methoxy-5-nitrobenzoic acid

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to example 547b from methyl 4-acetylamino-2-methoxy-5-nitro-benzoate with NaOH in ethanol.

Sources & evidence

ORD record: ord-211ecd1398b542d19d2005eef7183eed
Source dataset: uspto-grants-2015_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09040565B2

Reaction notes

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