Sodium Hydroxide → 2-Methoxy-4-(methylamino)-5-nitrobenzoic acid

HRID 578068Notes

Reaction equation

HRID 578068 reaction equation

C[O:2][C:3](=[O:20])[C:4]1[CH:9]=[C:8]([N+:10]([O-:12])=[O:11])[C:7]([N:13](C(=O)C)[CH3:14])=[CH:6][C:5]=1[O:18][CH3:19].[OH-].[Na+]>C(O)C>[CH3:19][O:18][C:5]1[CH:6]=[C:7]([NH:13][CH3:14])[C:8]([N+:10]([O-:12])=[O:11])=[CH:9][C:4]=1[C:3]([OH:20])=[O:2]

Participants

4

Reactant 2

HCID 14798Sodium Hydroxide

HCID 10379023Methyl 2-methoxy-4-(N-methylacetamido)-5-nitrobenzoate

Product 1

HCID 109879372-Methoxy-4-(methylamino)-5-nitrobenzoic acid

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to example 547b from 4-(Acetyl-methyl-amino)-2-methoxy-5-nitro-benzoic acid methyl ester and NaOH in ethanol.

Sources & evidence

ORD record: ord-4e0d0ebc40b246debf99da9dc8320e41
Source dataset: uspto-grants-2015_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09040565B2

Reaction notes

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