Ethanol → Ethyl 4-amino-2-methoxy-5-nitrobenzoate

HRID 578069Notes

Reaction equation

HRID 578069 reaction equation
[NH2:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([O:14][CH3:15])[CH:3]=1.S(=O)(=O)(O)O.[CH2:21](O)[CH3:22]>>[NH2:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][C:5]([C:6]([O:8][CH2:21][CH3:22])=[O:7])=[C:4]([O:14][CH3:15])[CH:3]=1

Participants

4

Reactant 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 1010164-Amino-2-methoxy-5-nitrobenzoic acid

Product 1

HCID 67231122Ethyl 4-amino-2-methoxy-5-nitrobenzoate

Procedure

Prepared analogously to example 655a from 4-amino-2-methoxy-5-nitro-benzoic acid with conc. sulphuric acid in ethanol.

Sources & evidence

ORD record
ord-a5d14f5462b64d7ba1fc3338df2c68ae
Source dataset
uspto-grants-2015_05
Patent number
US09040565B2

Reaction notes

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