HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 3-(3-(Pyridin-3-yl)-1,2,4-oxadiazol-5-yl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 3-Sulfamoylbenzoic acid | HCID 229352 | — |
| Reactant | N-Hydroxynicotinimidamide | HCID 308113 | — |
| Product | 3-(3-(Pyridin-3-yl)-1,2,4-oxadiazol-5-yl)benzenesulfonamide | HCID 59758743 | — |
Reaction Steps
The title compound was prepared according to the procedure of Example 8 using N′-hydroxynicotinimidamide (Aldrich) and 3-sulfamoylbenzoic acid (Oakwood). 1H NMR (300 MHz, CD3OD) δ 7.65 (ddd, J=8.0, 4.9, 1.0 Hz, 1H), 7.83 (t, J=7.9 Hz, 1H), 8.21 (ddd, J=7.9, 1.8, 1.0 Hz, 1H), 8.45 (dt, J=7.9, 1.4 Hz, 1H), 8.58 (dt, J=8.0, 1.9 Hz, 1H), 8.73-8.77 (m, 2H), 9.31 (dd, J=2.2, 1.0 Hz, 1H) ppm; MS (DCI/NH3) m/z 303 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040568B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-68a5a82fa99246708320788a777334cb |
| Source note | uspto-grants-2015_05 |