Ammonia → HCID 59758754, compound

HRID 578121Notes

Reaction equation

HRID 578121 reaction equation
[OH:1][N:2]=[C:3]([NH2:10])[C:4]1[CH:9]=[CH:8][CH:7]=[N:6][CH:5]=1.[CH3:11][S:12]([C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][CH:23]=1)[C:18](O)=O)(=[O:14])=[O:13].N>>[CH3:11][S:12]([C:15]1[CH:16]=[C:17]([C:18]2[O:1][N:2]=[C:3]([C:4]3[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=3)[N:10]=2)[CH:21]=[CH:22][CH:23]=1)(=[O:13])=[O:14]

Participants

4

Reactant 3

HCID 222AmmoniaHCID 2203803-Methanesulfonylbenzoic acidHCID 308113N-Hydroxynicotinimidamide

Product 1

HCID 59758754HCID 59758754, compound

Procedure

The title compound was prepared according to the procedure of Example 8 using N′-hydroxynicotinimidamide (Aldrich) and 3-(methylsulfonyl)benzoic acid (Aldrich). 1H NMR (300 MHz, CD3OD) δ 3.24 (s, 3H), 7.65 (ddd, J=8.0, 4.9, 1.0 Hz, 1H), 7.89-7.96 (m, 1H), 8.28 (ddd, J=8.0, 1.9, 1.0 Hz, 1H), 8.55-8.61 (m, 2H), 8.75 (dd, J=5.1, 1.7 Hz, 1H), 8.78 (t, J=1.5 Hz, 1H), 9.32 (dd, J=2.2, 0.8 Hz, 1H) ppm; MS (DCI/NH3) m/z 302 (M+H)+.

Sources & evidence

ORD record
ord-4060d425703041de959fbec3d2886601
Source dataset
uspto-grants-2015_05
Patent number
US09040568B2

Reaction notes

Loading…