Ammonia → HCID 44544771, compound

HRID 578161Notes

Reaction equation

HRID 578161 reaction equation
[OH:1][N:2]=[C:3]([C:5]1[CH:10]=[CH:9][N:8]=[N:7][CH:6]=1)[NH2:4].[N:11]1[CH:16]=[C:15]([C:17](O)=O)[CH:14]=[N:13][CH:12]=1.N>>[N:8]1[CH:9]=[CH:10][C:5]([C:3]2[N:4]=[C:17]([C:15]3[CH:16]=[N:11][CH:12]=[N:13][CH:14]=3)[O:1][N:2]=2)=[CH:6][N:7]=1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 78346Pyrimidine-5-carboxylic acidHCID 136140373N-Hydroxy-4-pyridazinecarboximidamide

Product 1

HCID 44544771HCID 44544771, compound

Procedure

The titled compound was prepared according to the procedure of Method C using the product of Example 83D and pyrimidine-5-carboxylic acid (Maybridge). 1H NMR (300 MHz, CD3OD) δ 8.41 (dd, J=5.4, 2.4 Hz, 1H), 9.44 (s, 1H), 9.47 (dd, J=5.4, 1.4 Hz, 1H), 9.59 (s, 2H), 9.90 (dd, J=2.2, 1.2 Hz, 1H) ppm; MS (DCI/NH3) m/z=227 (M+H)+.

Sources & evidence

ORD record
ord-8988fa18412a4bd7b61ac5acf0083f37
Source dataset
uspto-grants-2015_05
Patent number
US09040568B2

Reaction notes

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