Ammonia → HCID 178420781, compound

HRID 578173Notes

Reaction equation

HRID 578173 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[N:3]=[N:2]1.O[N:14]=[C:15]([NH2:22])[C:16]1[CH:21]=[CH:20][CH:19]=[N:18][CH:17]=1.N>>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]3[O:12][N:22]=[C:15]([C:16]4[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=4)[N:14]=3)=[CH:9][C:4]=2[N:3]=[N:2]1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 308113N-HydroxynicotinimidamideHCID 178524184HCID 178524184, compound

Product 1

HCID 178420781HCID 178420781, compound

Procedure

The title compound was prepared according to Method C using 1H-benzo[d][1,2,3]triazole-5-carboxylic acid (Aldrich) and N′-hydroxynicotinimidamide (Tyger). 1H NMR (300 MHz, DMSO-d6) δ 7.67 (ddd, J=8.0, 4.9, 0.7 Hz, 1H), 8.10-8.20 (m, 1H), 8.22-8.31 (m, 1H), 8.49 (dt, J=8.1, 2.0, 1.7 Hz, 1H), 8.75-8.92 (m, 2H), 9.30 (dd, J=2.2, 0.8 Hz, 1H) ppm; MS (DCI/NH3) m/z 265 (M+H)+.

Sources & evidence

ORD record
ord-395073862dd94743a370161603088379
Source dataset
uspto-grants-2015_05
Patent number
US09040568B2

Reaction notes

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