HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-(Benzo[d]thiazol-5-yl)-3-(pyridin-3-yl)-1,2,4-oxadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | N-Hydroxynicotinimidamide | HCID 308113 | — |
| Reactant | 1,3-Benzothiazole-5-carboxylic acid | HCID 2735460 | — |
| Product | 5-(Benzo[d]thiazol-5-yl)-3-(pyridin-3-yl)-1,2,4-oxadiazole | HCID 44544963 | — |
Reaction Steps
The title compound was prepared according to Method C using benzo[d]thiazole-5-carboxylic acid (Apollo) and N′-hydroxynicotinimidamide (Tyger). 1H NMR (300 MHz, DMSO-d6) δ 7.64-7.73 (m, 1H), 8.35 (s, 1H), 8.36 (s, 1H), 8.48 (dt, J=8.1, 2.0, 1.7 Hz, 1H), 8.83 (dd, J=4.7, 1.7 Hz, 1H), 9.17 (t, J=1.2 Hz, 1H), 9.29 (dd, J=2.2, 0.8 Hz, 1H), 9.66 (s, 1H) ppm; MS (DCI/NH3) m/z 281 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040568B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-69a988413bfe4068a9e017e608224770 |
| Source note | uspto-grants-2015_05 |