化工社化工社 化学情報印刷レポート · 研究参考用
Ammonia → 5-(1-methyl-1H-benzo[d]imidazol-5-yl)-3-(pyridin-3-yl)-1,2,4-oxadiazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | N-Hydroxynicotinimidamide | HCID 308113 | — |
| 反応物 | 1-Methyl-1H-benzimidazole-5-carboxylic acid | HCID 4913063 | — |
| 生成物 | 5-(1-methyl-1H-benzo[d]imidazol-5-yl)-3-(pyridin-3-yl)-1,2,4-oxadiazole | HCID 44544967 | — |
反応手順
The title compound was prepared according to Method C using 1-methyl-1H-benzo[d]imidazole-5-carboxylic acid (Maybridge) and N′-hydroxynicotinimidamide (Tyger). 1H NMR (300 MHz, DMSO-d6) δ7.65 (ddd, J=8.0, 4.9, 0.7 Hz, 1H), 7.68-7.88 (m, J=8.8 Hz, 1H), 7.87-8.10 (m, 2H), 8.14-8.37 (m, 1H), 8.46 (dt, J=8.1, 1.9 Hz, 1H), 8.82 (dd, J=4.7, 1.7 Hz, 1H), 9.27 (dd, J=2.0, 0.7 Hz, 1H) ppm; MS (DCI/NH3) m/z 278 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09040568B2 |
| 出典データセット | uspto-grants-2015_05 |
| ORD ID | ord-8b395f5039074ac4a20b585532b8b7a5 |
| 出典メモ | uspto-grants-2015_05 |