HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 3-(Imidazo[1,2-a]pyridin-6-yl)-5-(pyridin-3-yl)-1,2,4-oxadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Nicotinoyl chloride | HCID 82604 | — |
| Reactant | N'-hydroxyimidazo[1,2-a]pyridine-6-carboximidamide | HCID 2764575 | — |
| Product | 3-(Imidazo[1,2-a]pyridin-6-yl)-5-(pyridin-3-yl)-1,2,4-oxadiazole | HCID 44545064 | — |
Reaction Steps
The title compound was prepared according to Method D using N′-hydroxyimidazo[1,2-a]pyridine-6-carboximidamide (Bionet) and nicotinoyl chloride, hydrochloric Acid (Aldrich). 1H NMR (300 MHz, DMSO-d6) δ 7.62-7.91 (m, 4H), 8.20 (s, 1H), 8.56 (dt, J=8.1, 1.9 Hz, 1H), 8.92 (dd, J=4.7, 1.7 Hz, 1H) ppm; MS (DCI/NH3) m/z 264 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040568B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-aca15a6eeafd4dea961dda7abbf72619 |
| Source note | uspto-grants-2015_05 |