HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-(6-Fluoropyridin-3-yl)-3-(imidazo[1,2-a]pyridin-6-yl)-1,2,4-oxadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 6-Fluoronicotinic Acid | HCID 242819 | — |
| Reactant | N'-hydroxyimidazo[1,2-a]pyridine-6-carboximidamide | HCID 2764575 | — |
| Product | 5-(6-Fluoropyridin-3-yl)-3-(imidazo[1,2-a]pyridin-6-yl)-1,2,4-oxadiazole | HCID 44545066 | — |
Reaction Steps
The title compound was prepared according to Method C using N′-hydroxyimidazo[1,2-a]pyridine-6-carboximidamide (Bionet) and 6-fluoronicotinic acid (Frontier). 1H NMR (300 MHz, DMSO-d6) δ 7.55 (ddd, J=8.5, 2.7, 0.7 Hz, 1H), 7.70 (d, J=1.4 Hz, 1H), 7.73-7.86 (m, 2H), 8.20 (s, 1H), 8.75 (ddd, J=8.1, 2.5 Hz, 1H), 9.08 (dt, J=1.7, 0.8 Hz, 1H), 9.46 (dd, J=1.7, 1.0 Hz, 1H) ppm; MS (DCI/NH3) m/z 282 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040568B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-353d3c4252bb403d8a3e81849c9a11d7 |
| Source note | uspto-grants-2015_05 |