Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Tert-butyl-5-(4-methylpiperidin-1-yl)-6-nitrobenzothiazole → 6-Amino-2-tert-butyl-5-(4-methylpiperidin-1-yl)benzothiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Tert-butyl-5-(4-methylpiperidin-1-yl)-6-nitrobenzothiazole | HCID 19794189 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 6-Amino-2-tert-butyl-5-(4-methylpiperidin-1-yl)benzothiazole | HCID 19794186 | — |
반응 단계
A solution of 15.2 g of 2-tert-butyl-5-(4-methyl-piperidin-1-yl)-6-nitrobenzothiazole in 600 ml of methanol is hydrogenated in presence of 6.5 g of Raney Nickel at room temperature. After removing the catalyst the solution is concentrated and the solid filtered to give 6-amino-2-tert-butyl-5-(4-methylpiperidin-1-yl)benzothiazole melting at 146°-148°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05246927 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-d2d2589cd1d140879dce79874d0e6100 |
| 출처 메모 | uspto-grants-1993_09 |