HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ether hydrochloride → HCID 66763600, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ether hydrochloride | HCID 10953452 | — |
| Reactant | HCID 66761899 | HCID 66761899 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 66763600 | HCID 66763600 | 95% |
Reaction Steps
The title compound was prepared as light yellow solid in 95% yield by treating tert-butyl [4-({[8-(aminocarbonyl)quinazolin-4-yl]amino}methyl)phenyl]carbamate with 2N HCl/ether in DCM overnight. The precipitate was filtered, washed with ether and dried. Mass: M+H+: 294.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040560B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-07db9e42b3614941b918b738103a1139 |
| Source note | uspto-grants-2015_05 |