Sodium Hydroxide → HCID 66763337, compound

HRID 578680Notes

Reaction equation

C([O:3][C:4]([C:6]1[O:10][C:9]([NH:11][C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([CH:18]([NH:20][C:21]3[C:30]4[C:25](=[C:26]([C:31](=[O:33])[NH2:32])[CH:27]=[CH:28][CH:29]=4)[N:24]=[CH:23][N:22]=3)[CH3:19])[CH:13]=2)=[N:8][CH:7]=1)=[O:5])C.[OH-].[Na+]>>[C:31]([C:26]1[CH:27]=[CH:28][CH:29]=[C:30]2[C:25]=1[N:24]=[CH:23][N:22]=[C:21]2[NH:20][CH:18]([C:14]1[CH:13]=[C:12]([NH:11][C:9]2[O:10][C:6]([C:4]([OH:5])=[O:3])=[CH:7][N:8]=2)[CH:17]=[CH:16][CH:15]=1)[CH3:19])(=[O:33])[NH2:32]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 66763795HCID 66763795, compound

Product 1

HCID 66763337HCID 66763337, compound

Procedure

The ester was hydrolyzed with 1N NaOH at 60° C. for 2 h to get the title compound. LCMS (M+1) 419.

Sources & evidence

ORD record: ord-c4311ef70d594cc6b49b6f5f13692dd3
Source dataset: uspto-grants-2015_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09040560B2

Reaction notes

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