HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-chlorooxazole-4-carboxylate → 2-{3-[(8-Carbamoyl-quinazolin-4-ylamino)-methyl]-phenylamino}-oxazole-4-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-chlorooxazole-4-carboxylate | HCID 2763184 | — |
| Reactant | 4-(3-Amino-benzylamino)-quinazoline-8-carboxylic acid amide hydrochloride | HCID 66763358 | — |
| Product | 2-{3-[(8-Carbamoyl-quinazolin-4-ylamino)-methyl]-phenylamino}-oxazole-4-carboxylic acid ethyl ester | HCID 66762747 | — |
Reaction Steps
The title compound was prepared according to Example 684 starting 4-(3-Amino-benzylamino)-quinazoline-8-carboxylic acid amide hydrochloride and 2-Chloro-oxazole-4-carboxylic acid ethyl ester at 120° C.:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040560B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-fd62a76de0594cb485d5dfa6ed1f9803 |
| Source note | uspto-grants-2015_05 |