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4-chloro-1-methyl-1H-imidazo(4,5-c)pyridine → 4-[3-(1-Methyl-1H-imidazo[4,5-c]pyridin-4-ylamino)-benzylamino]-quinazoline-8-carboxylic acid amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-chloro-1-methyl-1H-imidazo(4,5-c)pyridine | HCID 948792 | — |
| 反応物 | 4-(3-Amino-benzylamino)-quinazoline-8-carboxylic acid amide hydrochloride | HCID 66763358 | — |
| 生成物 | 4-[3-(1-Methyl-1H-imidazo[4,5-c]pyridin-4-ylamino)-benzylamino]-quinazoline-8-carboxylic acid amide | HCID 66762191 | — |
反応手順
The title compound was prepared according to Example 549 starting 4-(3-Amino-benzylamino)-quinazoline-8-carboxylic acid amide hydrochloride and 4-Chloro-1-methyl-1H-imidazo[4,5-c]pyridine. Reaction conditions: 120° C. in the microwave for 10 h:
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09040560B2 |
| 出典データセット | uspto-grants-2015_05 |
| ORD ID | ord-059bc6a5791541068d83cb0a95f591a7 |
| 出典メモ | uspto-grants-2015_05 |