Potassium Carbonate → HCID 58022035, compound

Participants

Reaction Steps

To a solution of 2-fluoro-5-mercaptoaniline (0.13 g) and 2-fluorobenzyl bromide (0.12 mL) in N,N-dimethylformamide (5 mL) was added potassium carbonate (0.25 g), and the mixture was stirred at room temperature for 30 minutes. The reaction mixture was diluted with diethyl ether, and the resulting mixture was washed with water twice and brine successively, and dried over anhydrous magnesium sulfate. The solvent was removed under reduced pressure, and the residue was purified by column chromatography on silica gel (eluent: n-hexane/ethyl acetate =6/1) to give the title compound (0.17 g).

Provenance & Evidence