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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 578836Generated: October 26, 2026

4-Nitrophenylboronic acid → (4-{[5-(3-Chlorophenyl)-6-methoxypyridin-3-yl]methyl}phenyl)urea

https://huagongshe.com/reaction/578836

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitrophenylboronic acidHCID 2773552—
Reactant5-(Bromomethyl)-3-(3-chlorophenyl)-2-methoxypyridineHCID 90416258—
Reactant3-(3-Chlorophenyl)-2-methoxy-5-(4-nitrobenzyl)pyridineHCID 90416785—
Product(4-{[5-(3-Chlorophenyl)-6-methoxypyridin-3-yl]methyl}phenyl)ureaHCID 86304115—

Reaction Steps

3-(3-Chlorophenyl)-2-methoxy-5-(4-nitrobenzyl)pyridine. The title compound was prepared in a manner analogous to Example 1, from Intermediate 2 and 4-nitrophenyl boronic acid to afford a tan solid. [M+H]=355.07.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09040692B2
Source datasetuspto-grants-2015_05
ORD IDord-5ec52bcf5bf04639a94d6d1ace809695
Source noteuspto-grants-2015_05