反应详情

The title compound was prepared in a manner similar to Example 112 using 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinic acid and 3-(1H-pyrazol-1-yl)propan-1-amine 1H NMR (400 MHz, DMSO-d6) δ ppm 2.00-2.10 (m, 2 H) 3.25-3.30 (m, 2 H) 4.19 (t, J=6.95 Hz, 2 H) 6.23 (t, J=2.02 Hz, 1 H) 7.45 (d, J=1.77 Hz, 1 H) 7.77 (d, J=1.52 Hz, 1 H) 7.79 (d, J=8.59 Hz, 2 H) 8.14 (d, J=7.33 Hz, 2 H) 8.37-8.44 (m, 1 H) 8.45-8.58 (m, 1 H) 8.66 (br. s., 1 H) 8.74 (t, J=5.31 Hz, 1 H) 8.88-8.94 (m, 1 H) 13.54 (br. s., 1 H). MS m/z [M+H]+ 414.2.