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HRID578987

反应详情

EQUATION

反应方程式

HRID 578987 的结构方程式

REACTANTS

反应物

2
结构：CC[C@H](C)N
HCID6713753

(2S)-2-Butanamine

C4H11N

结构：Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)O)cn2)c1O
HCID178426451

未命名化合物

PRODUCTS

生成物

1
结构：CC[C@H](C)NC(=O)c1ccc(-n2ncc(-c3ccc(C#N)cc3C)c2O)nc1
HCID178456040

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in a manner similar to Example 112 using 6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinic acid and (S)-butan-2-amine 1H NMR (400 MHz, DMSO-d6) δ ppm 0.90 (t, J=7.33 Hz, 3 H) 1.17 (d, J=6.57 Hz, 3 H) 1.46-1.63 (m, 2 H) 2.44 (s, 3 H) 3.95 (dt, J=13.83, 7.11 Hz, 1 H) 7.67 (dd, J=8.08, 1.26 Hz, 1 H) 7.74 (s, 1 H) 7.78 (br. s., 1 H) 8.17 (br. s., 1 H) 8.32-8.58 (m, 3 H) 8.87-8.95 (m, 1 H) 13.18 (br. s., 1 H). MS m/z [M+H]+ 376.2.