Isopropylamine → HCID 178426434, compound

Participants

Reaction Steps

The title compound was prepared in a manner similar to Example 112 using 6-(4-(4-cyano-2-methylphenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinic acid and isopropylamine 1H NMR (400 MHz, DMSO-d6) δ ppm 1.20 (d, J=6.57 Hz, 6 H) 2.44 (s, 3 H) 4.13 (dd, J=14.15, 6.57 Hz, 1 H) 7.66 (dd, J=8.08, 1.52 Hz, 1 H) 7.74 (s, 1 H) 7.75-7.85 (m, 1 H) 8.07-8.28 (m, 1 H) 8.45 (dd, J=19.70, 6.82 Hz, 3 H) 8.84-8.98 (m, 1 H) 12.97-13.37 (m, 1 H). MS m/z [M+H]+ 362.2.

Provenance & Evidence