反应详情

The title compound was prepared in a manner similar to Example 198 using 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)nicotinic acid and 1-(2-methoxyethyl)cyclopropanamine 1H NMR (400 MHz, DMSO-d6) δ ppm 0.58-0.73 (m, 4 H) 1.79 (t, J=6.9 Hz, 2 H) 3.14 (s, 3 H) 3.39 (t, J=6.9 Hz, 2 H) 7.72 (d, J=8.6 Hz, 2 H) 8.07 (d, J=7.8 Hz, 2 H) 8.27-8.34 (m, 1 H) 8.37 (br. s., 1 H) 8.57 (br. s., 1 H) 8.77 (s, 1 H) 8.79-8.83 (m, 1 H) 13.46 (br. s., 1 H). MS m/z 404 [M+H]+.