反应详情

The title compound was prepared in a manner similar to Example 212 using 6-(4-bromo-5-methoxy-1H-pyrazol-1-yl)-N-(3-methoxypropyl)nicotinamide and (2-methoxy-6-methylpyridin-4-yl)boronic acid. 1H NMR (400 MHz, DMSO-d6) δ ppm 1.71 (quin, J=6.6 Hz, 2 H) 2.30 (s, 3 H) 3.18 (s, 3 H) 3.22-3.30 (m, 2 H) 3.32 (t, J=6.3 Hz, 2 H) 3.79 (s, 3 H) 7.16 (br. s., 1 H) 7.31 (br. s., 1 H) 8.31 (br. s., 1 H) 8.33-8.53 (m, 2 H) 8.61 (br. s., 1 H) 8.82 (s, 1 H) 13.35 (br. s., 1 H). MS m/z 398 [M+H]+.