2-Ethoxypyridine-4-boronic acid → HCID 178466015, compound

Participants

Reaction Steps

The title compound was prepared in a manner similar to Example 213 using 6-(4-bromo-5-methoxy-1H-pyrazol-1-yl)-N-(3-methoxypropyl)nicotinamide and (2-ethoxypyridin-4-yl)boronic acid. 1H NMR (400 MHz, DMSO-d6) δ ppm 1.25 (t, J=7.1 Hz, 3H) 1.71 (quin, J=6.7 Hz, 2 H) 3.18 (s, 3 H) 3.21-3.29 (m, 2 H) 3.32 (t, J=6.3 Hz, 2 H) 4.22 (q, J=7.1 Hz, 2 H) 7.31 (s, 1 H) 7.40 (d, J=5.3 Hz, 1 H) 7.94 (d, J=5.6 Hz, 1 H) 8.26-8.34 (m, 1 H) 8.34-8.42 (m, 1 H) 8.47 (br. s., 1 H) 8.61 (t, J=5.6 Hz, 1 H) 8.82 (d, J=1.5 Hz, 1 H) 13.42 (br. s., 1 H). MS m/z 398 [M+H]+.

Provenance & Evidence